Molecular genetic diagnosis of sickle cell disease using dried blood specimens on blotters used for newborn screening The protein-based technologies used to screen newborns for sickle cell disease require confirmation with a liquid blood specimen. We have developed a strat... David,C.,Jinks,... ...
Blood transfusion remains an important therapeutic intervention in patients with sickle cell disease (SCD), aiming to both increase the oxygen carrying capacity of blood and to reduce the complications of vaso-occlusion. Simple, manual exchange and automated exchange can be effective in reducing the ...
Sickle cell disease (SCD) is a family of inherited red blood cell disorders that occur when hemoglobin—the protein in red blood cells that carries oxygen throughout your body—takes on a C, or sickled, shape, instead of a healthy oval shape. Cells become hard and sticky, blocking blood ...
Silent cerebral infarcts occur despite regular blood transfusion therapy after first strokes in children with sickle cell disease. Children with sickle cell disease (SCD) and strokes receive blood transfusion therapy for secondary stroke prevention; despite this, approximately 20% expe... ML Hulbert,RC...
Sickle cell disease (SCD) leads to significant morbidity and early mortality, and hematopoietic cell transplantation (HCT) is the only widely available cure, with impacts seen on SCD-related organ dysfunction. Outcomes are excellent following matched related donor (MRD) HCT, leading to significantly ...
to block blood flow in tiny blood vessels. Not all patients with sickle cell disease experience vaso-occlusion, and the frequency of attacks can vary widely between patients. The MIT researchers hope that their findings may help them to devise a way to predict these crises for individual ...
Since not all patients with sickle cell disease experience vaso-occlusion and the frequency of attacks can vary widely between patients, the MIT researchers hope that their findings may help them to devise a way to predict these crises for individual patients....
Research into sickle cell disease is personal, Hyacinth said, as his nephew has SCD and he and his son both havesickle cell trait. People with sickle cell trait inherit one sickle cell gene from a parent and typically do not have symptoms of SCD, but they can pass the trait on to their...
作者: B Disease 摘要: Recognizing that you're anemic can be challenging. Symptoms are often subtle or vary with the underlying cause. At the same time, your body is capable of adjusting amazingly well to slowly developing anemia to further mask its signs. Anemia means that the number of ...
Sickle cell anemia– People with sickle cell disease (SCD) have red blood cells shaped like a sickle. This causes the RBC to stick together and block blood flow to body parts such as the eyes. Blocked blood vessels cause pressure to build up, causing the vessels to burst and bleed resulti...