(2012) Allogeneic cellular and autologous stem cell therapy for sickle cell disease: ‘whom, when and how’. Bone Marrow Transplantation 47 , 1489-1498 /Freed J, Talano J, Small T, Ricci A, Cairo MS. Allogeneic cellular and autolo gous stem cell therapy for sickle cell disease: `...
Disease-modifying treatments (DMTs) can help lessen pain from low blood oxygen levels. And two new, FDA-approved gene therapies may help end hospitalizations for SCD pain forever.
Pediatric Research publishes original papers, invited reviews, and commentaries on the etiologies of diseases of children and disorders of development, extending from molecular biology to epidemiology. Use of model organisms and in vitro techniques relevant to developmental biology and medicine are ...
In 2023, 2 different gene therapies were approved for individuals with severe sickle cell disease (SCD). The small number of patients treated on the pivotal clinical trials that led to these approvals have experienced dramatic short-term reductions in the occurrence of painful vaso-occlusive crises...
Fifty years ago, people with sickle cell disease (SCD) were discouraged from becoming pregnant, but now, most should be supported if they choose to pursue a pregnancy. They and their providers, however, should be aware of the physiological changes of pregnancy that aggravate SCD and pregnancy’...
23-25 January 2013 Sickle cell disease is the most prevalent monogenic disor- der worldwide resulting from single DNA mutation in beta globin gene. The mapping on the pattern of its distri- bution in India has been studied to a great extent. How- ever paucity of adequate data throughout ...
Take this quiz and test your IQ of high blood pressure (hypertension), the cardiovascular disease that causes most strokes and heart attacks. How are dizziness, snoring, and gout related to HBP? Find... High Blood Pressure Treatment High blood pressure (hypertension) means high pressure (tension...
Since not all patients with sickle cell disease experience vaso-occlusion and the frequency of attacks can vary widely between patients, the MIT researchers hope that their findings may help them to devise a way to predict these crises for individual patients....
That made it difficult to understand trends or allocate resources effectively. So the foundation helped create the Institute for Health Metrics and Evaluation at the University of Washington, to give a permanent home to the Global Burden of Disease study—originally developed in the 1990s by ...
Wen:A number of factorsincrease stroke risk. It may help to think of them in three categories. First are medical conditions, such as a previous stroke or TIA, high blood pressure, diabetes, high cholesterol, sickle cell disease and obesity. Several heart disorders ...