Also, diphyllin and bafilomycin loaded Polyethylene glycol (PEG)-PLGA diblock polymers were used against influenza [33]. These formulations enhanced the therapeutic index of these agents by 3 and 5 fold, respectively, and also enabled the sustained release of them for more than three days. Low ...
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The design principle is similar to the Protopic® ointment, where propylene carbonate instead of propylene glycol is dispersed as a solvent for the API in the ointment matrix in the form of an “oil-in-oil” emulsion [23]. The reasons to choose this approach may be solubility (e.g., ...