A skin-cancer cell. Cells might rely on cues from their internal skeletons to expand without becoming cancerous. Credit: Steve Gschmeissner/SPL A cell controls its volume by keeping tabs on the tension of its internal ‘skeleton’, experiments suggest. ...
A protein called YAP might help to convey messages from a cell's internal framework.#A protein called YAP might help to convey messages from a cell's internal framework.#Skin cancer cell, coloured scanning electron micrograph.Nature Publishing Group UKNature...
In 2005, Joan Massagué at the Memorial Sloan-Kettering Cancer Center in New York identified a roster of genes that seem to help breast cancer cells to metastasize to the lung1. Now Massagué's team has shown how four of these genes specifically work in concert to fuel metastasis. Addressin...
The team designed experiments to observeprostate cancercells every two hours, discovering that these signals were triggered between four and eight hours after treatment. By 72 hours after treatment, the targeted cells were either dead or growing again. Treating patients with an inhibitor of Notch in...
Chemotherapyis one of the most common treatments for cancer. It uses certain drugs to kill cancer cells or to stop them from growing and spreading to other parts of your body. Your doctor might prescribe chemo by itself or with surgery orradiation therapy. You might also take newer kinds of...
When they silenced the gene for MTOR—a stress sensor protein—they discovered that cancer cells stopped growing, but paradoxically accelerated evolution in the presence of a cancer treatment. "MTOR is a sensor protein that tells normal cells to stop growing because there is a stress in the envi...
are “recognized” as faulty. However, there are times, especially as humans age, when the immune system can’t clear the cells. Left alone to meander in the body, the abnormal cells can replicate their genome again, shuffle the chromosomes at the next division, and a growing cancer begins...
But sometimes, the process gets disrupted, causing cells to multiply too quickly. This results in cancer. Chemotherapy targets these fast-growing cancer cells. The drugs kill these cells or at least stop them from multiplying. They do this by interrupting certain parts of the cell cycle. Each ...
Your doctor will suggest a targeted therapy based on your cancer cells. You could get the medicine as an injection, through an IV, or as a pill. Abemaciclib (Verzenio) It curbs the activity of CDK4 and CDK6 enzymes, which helps stop cancer cells from dividing and growing. ...
When telomeres are too short, some cells turn into cancer. Cancerous cells have the ability to prevent their telomeres from getting shorter by activating telomerase. If telomerase makes cancer cells immortal, how would the administration of telomerase prevent normal cells from becoming cancero...