When pollen floats through the air and reaches the nose, the body sometimes overreacts. Mast cells in the lining of the nose mistake the harmless tree particles for dangerous invaders. They summon help by releasing chemicals such as histamine and tryptase, which then recruit more immune system c...
In this theory, MCs would reduce the dermal availability of dopamine to interfere with its paracrine and autocrine function, but they may also act in a timely shifted pattern of dopamine release (Figure 4). Further studies will be required to more precisely assess the position of MCs in the ...