Barriot R, Sherman DJ, Dutour I (2007) How to decide which are the most pertinent overlyrepresented features during gene set enrichment analysis . BMC Bioinformatics 8 : 332.R. Barriot, D. J. Sherman, and I. Dutour, “How to decide which are the most pertinent overly-represented ...
Recent evidence has elucidated how multipotent blood progenitors transform their identities in the thymus and undergo commitment to become T cells. Together with environmental signals, a core group of transcription factors have essential roles in this pr
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gene expression. The SNP-gene associations are tissue specific; hence we can estimate what genes are more highly associated with a disease at the tissue level. Part 2 conducts eMAGMA gene-set analysis, testing for the enrichment of association in co-expression networks. The aim of this ...
It’s for kids in nursery or pre-school, so from three-and-a-half to four-and-a-half - the year before they enter formal education. It’s a whole-class language enrichment programme, built around repeated reading of a set of early reading books. It’s basically 20 to 30 minute...
Differentially regulated genes (GEA model) were subjected to enrichment analysis to select GO terms "enriched with" these genes. Two broad GO categories included are "Biological Process" and "Molecular Function". Specific GO terms are included and specific genes within each gene term differentiating ...
Housekeeping (HK) genes are ubiquitously expressed in all tissue/cell types and constitute a basal transcriptome for the maintenance of basic cellular functions. Partitioning transcriptomes into HK and tissue-specific (TS) genes relatively is fundamental
While read coverage of annotated E. coli genes was nearly complete in the 156M read dataset, the possibility of gDNA contamination raised concern that some of these genes were not actually transcribed. To better estimate the proportion of E. coli genes transcribed under the conditions tested, we...
Figure 4: GO enrichment of PSGs related to ecological adaptation inC.himalaica. The Arabic numbers show the enriched number of PSGs in each term. Full size image In addition, GO annotation also showed that many PSGs are related to specific adaptation traits, including nitrogen compound metabolic...
To set the scene, in particular for readers without firsthand experience with children from socioeconomically challenging circumstances, we first describe our decades-long investigative endeavor that revealed the pervasive effects of poverty on poor inner-city children, and the young ages at which ...