SiRNA (small interfering RNA) therapy can treat some health conditions by changing how some of your genes work. A new medication called inclisiran (Leqvio) uses this technology to treat adults with heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD...
The footprint (size), complexity, capabilities, and cost of cell counters also vary widely. If you're using an automated cell counter, get familiar with the manufacturer’s instructions on how to prepare samples, what volume to load, any special requirements for your cell type, and any softw...
The evolution from CHIP to neoplasia occurs as the result of further mutations in cells capable of self-renewal. CHIP mutations that affect epigenetic coordination of commitment are likely to prepare the ground for neoplastic progression firstly by increasing mutation rate (for instance by affecting th...