The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is a candidate vaccine antigen that binds angiotensin-converting enzyme 2(ACE2), leading to virus entry. Here, it is shown that rapid conversion of recombinant RBD into particulate form via admixing with liposomes containing ...
Visualization of the virus’ spike protein (cyan) surrounded by mucus molecules (red) and calcium ions (yellow). The viral membrane is shown in purple. Credit: UC San Diego’s Lorenzo Casalino, the Amaro Lab, and the research team. UC San Diego develops computer model to aid understanding ...
If we had to simplify diet imperatives to a point, it would be to eat in a way that keeps your blood sugar stable throughout the day, meaning no naked carb loading (“naked” carbs are those consumed without fat or protein that mitigate the blood sugar spike), highly processed foods, o...
Antibodies, small proteins produced by the immune system, can attach to specific parts of avirusto neutralize it. As scientists continue to battleSARS-CoV-2, thevirus that causesCOVID-19, one possible weapon is a synthetic antibody that binds with the virus’ spike pro...
Bamlanivimab is a neutralizing IgG1 monoclonal antibody (mAb) directed against the spike protein of SARS-CoV-2. It is designed to block viral attachment and entry into human cells, which should neutralize the virus, and potentially prevent and treat COVID-19. ...
These new variants are a result of the accumulation of mutations in the sequence and structure of spike (S) glycoprotein, which is by far the most critical protein for SARS-CoV-2 to recognize cells and escape the immune system, in addition to playing a role in SARS-CoV-2 infection, ...
A detailed literature search has been conducted on PubMed for collecting information pertaining to the COVID-19; the history, origin, key structural features, and mechanism of infection of SARS-CoV-2; the repurposed drugs in use for the management of COVID-19, and the anti-inflammatory role...
Many microbes appeared equipped to protect themselves against colibactin. Balskus’s lab identified a resistance gene encoding a protein that neutralizes the compound in a wide variety of bacteria. Though colibactin clearly has a dangerous side, it may serve as more than just a lethal...
individuals who have recovered from an infectious disease, rich in antibodies against the pathogen responsible for their illness. This plasma is transfused into patients still fighting the infection, with the goal of leveraging the immune response of the recovered person to help accelerate the...
This tiny virus has wreaked havoc on people’s lives, killed people, and created psychological problems all over the world. The viral spike protein (S) significantly contributes to host cell entry, and mutations associated with it, particularly in the receptor-binding protein (RBD), either ...