Metabolites belong to amino acids, organic acids, cinnamates, alkaloids, flavonoids, pterocarpans, alkyl glycosides, sesquiterpenes, saponins, lignans, fatty acids/amides, and lysophospholipids, including several first-time reported metabolites and classes in Cucurbitaceae. Aroma profiling detected 93 ...
The rotation of the αC-helix is often used in MD studies to classify the resultant structures into either active or inactive [29]. Although the αC-helix positioning and salt-bridge presence are necessary for the full activation of the protein, they are not sufficient. The C-terminal lobe...