Of note is the fact that none for the males have been clinically determined to have hypogonadism (low testosterone) in past times, and none had been on medicines that may have impacted testosterone amounts. The scientists then measured the clients’ total testosterone, estradiol, intercourse hormon...
Estradiol levels modulate brain activity and negative responses to psychosocial stress across the menstrual cycle. Psychoneuroendocrinology 59: 14–24. Arnold AP (2009). The organizational-activational hypothesis as the foundation for a unified theory of sexual differentiation of all mammalian tissues. ...
A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with the pathogenesis of other viral infections. Biological sex differences may manifest themselves in susceptibility to infection, early pathogenesis, innate viral control, adaptive immune responses or the balance of ...
where one of the two X chromosomes in each cell is switched off to equalize X chromosome dosage with males. This process is regulated by a gene calledXIST, which produces a long non-coding RNA. XIST helps to form a complex of RNA and proteins that silence the inactive X chromosome (Xi)...
(e) Prenatal stress contributes to risk for diseases that exhibit sex differences across the life span (Goldstein et al, 2014). (f) Mid-life is associated with marked hormonal shifts for women, but not men. Estradiol effects on stress responses varies in pre- vs post-menopausal women (...
with high testosterone levels were Acinetobacter (phylum Proteobacteria), Dorea (phylum Firmicutes), Ruminococcus (phylum Firmicutes), and Megamonas (phylum Firmicutes) in men, while Slackia (phylum Actinobacteria) and Butyricimonas (phylum Bacteroidetes) correlated with high estradiol levels in women. Hi...
A diet with low glycemic index has been shown to extend lifespan in mice, which might be especially crucial considering the diminished ability of the body to regulate glucose levels with age. In case of protein intake, it seems that not only the amount but also the protein source, i. e....
Shalender Bhasin, MD and Karen Herbst, MD, PHD Studies in LDL receptor-deficient mice provide compelling evidence that testosterone retards early atherogenesis, and that the effects of testosterone on atherogenesis are mediated through its conversion to estradiol in the vessel wall. ...
Concerning the use of gonadotropin-releasing hormone analogs (GnRH-a) among HL patients receiving BEACOPP therapy, the GHSG phase II trial was stopped after the interim analysis due to not detecting any differences between the treatment arms receiving estradiol, follicle-stimulating hormone and anti-...