A blood test called a liquid biopsy can't confirm a lung cancer diagnosis, but it can give your doctor important information about your cancer. "It can help identify the tumor's molecular [genetic] characteristics, guide treatment decisions, and, in some cases, detect early recurrence after tr...
Such persistent high failure rate raises several questions: Why 90% of clinical drug development fails despite implementation of many successful strategies in the past several decades? Did we overlook certain aspects of drug development process leading to high failure? How can we improve the success ...
The choice between a post-injection 3D SPECT or 2D planar acquisition will impact the duration of the acquisition. 2D planar acquisitions are quick to perform, especially for whole-body imaging (WB), but they involve organ overlap, which can lead to uncertainties in attenuation correction and seg...
Over the last two decades, the understanding of how dysregulated ion channels and transporters are involved in carcinogenesis and tumor growth and progression, including invasiveness and metastasis, has been increasing exponentially. The present review s
want to become posthumans. I want to encourage all humans to explore enhancing their health, intelligence and productivity. There is a real risk of being left behind if you do not do that. I also want all of humanity to share in an amazing, grand future, whether they choose to be trans...
Using the CellSearch assay, a spike of CTCs from 0 to 8 was observed in May 2008, which corresponded with disease progression (Fig. 2a). We simulated the count patterns observed when the frequency of blood sampling is halved, using alternate time points. Depending on the sampling dates ...
Precision medicine isn't in the distant future. Some examples of treatments already in use today include: Before a blood transfusion, doctors match the donor's blood to the recipient's to make sure the two are compatible. Trastuzumab(Herceptin), a breast cancer drug, is designed to treat wom...
Commonly used herbs, such as Salvia miltiorrhiza (Danshen) and Ligusticum chuanxiong (Chuanxiong), improve blood circulation, reduce inflammation, and have fewer side effects.Citation18–20 Consequently, TCM is often employed as adjuvant therapy to slow disease progression and enhance overall patient ...
Education on community oncology may be able to improve its application and adoption in solid tumors to improve the prognoses of patients. Damage response and repair Damage response and repair (DRR) gene alterations in DNA are associated with increased tumor-infiltrating lymphocytes, higher genomic ...
Currently, the treatment in advanced HER2+ BC is the combination of trastuzumab, pertuzumab, and the chemotherapy agent taxane [37]. High expression of HER2 promotes tamoxifen resistance and the addition of trastuzumab could improve the tamoxifen response [38]. ...