Touch:Gently press on the swollen area. If it feels puffy or leaves an indentation (pitting edema), this could be a sign of a significant injury or inflammation. 3. Test Range of Motion: Ankle Flexibility:Sit down with your legs extended. Try to point your toes (plantar flexion) and the...
It could also be peripheral edema. One of the first things I do in the office when someone says they're getting up at night to pass urine is lift up their trouser legs and see if they have pitting edema. I ask them: Do you have swelling in the legs? Do your shoes start to get ...
Grade 3 diarrhea (≥7 stools per day over baseline or need for hospitalization) is rare with BTK inhibitor therapy. In these cases, BTK inhibitors may be paused until diarrhea is reduced to grade 2 or lower. The drug can then be re-initiated at the same dose or the dose can be ...