Other clinicians might resume the chemotherapy regimen without modification aside from omitting pegasparaginase or might consider intensifying consolidation with high-dose methotrexate (ie, in protocols that use the Capizzi approach). However, this remains an important issue that will require additional ...
Pretreatment serum levels of anti-cyclic citrullinated peptide antibodies are associated with the response to methotrexate in recent-onset arthritis. Ann Rheum Dis 2008;67:1194–5. 60. Saleem B, Mackie S, Quinn M, et al. Does the use of tumour necrosis factor antagonist therapy in poor ...
Inflammatory cytokines IL-1 and IL-6 also modulate pro-oncogenic transcription factor STAT3, thereby increasing survival, proliferation, angiogenesis, invasion, and metastasis of cancer cells [23]. STAT3 was also known to be upregulated in many cancer patients, and the level of STAT3 was directly ...
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