We could crystallise PP-N190 and solve its structure at 1.5 Å resolution (PDB ID: 6ZP9; Supplementary Table1and Fig.3b), using phase information from SeMet derivative crystals. Ca2+ions were mandatory in the mother liquor to obtain crystals. As expected, the protein has a classical AEP...
SHMs of the VRC34 intermediates are mapped on the structure of VRC34.01 (PDB: 5I8H) shown in ribbon representation. The location of each SHM is indicated with a sphere and colored according to the paired intermediates. (B) Effect of single Ala or Gly mutation on the binding affinity of ...
Everyone knows they get their genes from their parents, but few would be aware that even before they were born a lot of essential cell death has shaped their development. The greater population, for the most part, is blissfully unaware that every day millions of their own cells die in a ...