CRISPR has been used to correct genetic disorders, such ascystic fibrosis and cataracts, in laboratory-grown cells and in lab animals. It has also shown recent success as a treatment for other conditions in human trials. Notably, the U.K. and the U.S. have bothapproved a CRISPR-based gen...
UK first to approve CRISPR treatment for diseases: what you need to know Alzheimer’s drug donanemab: what promising trial means for treatments Heralded Alzheimer’s drug works — but safety concerns loom Alzheimer’s drug slows mental decline in trial — but is it a breakthrough? How ...
Due to CRISPR's simplicity, researchers and scientists are using CRISPR across various applications including agriculture, diagnostics, biofuels, and most notably, cell and gene therapies for the treatment of disease in the clinic. SpCas9: The Workhorse CRISPR-Associated Nuclease Cas9 is currently the...
But using messenger RNA, or mRNA, to get the immune system to mount a prolonged and aggressive attack on cancer cells — while leaving healthy cells alone — has been a major challenge. Strand Therapeutics’ Innovative Approach The MIT spinout Strand Therapeutics is attempting to solve that prob...
However, with progressive updates to treatment guidelines, advocating lower LDL-C goals, a greater proportion of patients will require use of combination therapy to reach these targets. This will require treatment of dyslipidemia to become similar to that of hypertension and type 2 diabetes, in ...
occur for variety of reasons, including stress, triggers, or a lack of social support. However, it's important to understand that relapse doesn't mean failure or a lack of willpower. Rather, it's a sign that adjustments need to be made to the treatment plan to ensure long-term ...
Stunning advances in gene research and data mining will predict diseases and devise treatments tailored to each of us.
In Japan, where the waiting period for heart transplantation is long, LVADs are particularly important as a bridge to transplantation. Recently, the use of LVADs as the main treatment for patients who are not candidates for heart transplantation has become increasingly important. This LVAD treatment...
The FDA had earlier granted Regenerative Medicine Advanced Therapy designation to nex-z for the treatment of ATTRv-PN. Intellia is also developing its wholly-owned NTLA-2002, an investigational in vivo CRISPR-based therapy designed to knock out the KLKB1 gene in the liver and enable lifelong co...
Last November, the UK became the first country to approve a treatment using Crispr technology, based on the bacterial immune system, for sickle cell disease. In January, Japan’s sovereign development bank invested in UK life sciences for the first time through 4Bio Capital, a UK venture fund...