(DAA) era for hepatitis C virus (HCV) infection, sustained virological response (SVR) is very high, but close attention must be paid to the possible occurrence of hepatocellular carcinoma (HCC) and reactivation of hepatitis B virus (HBV) in patients with co-infection who achieved SVR in ...
Secreted protein acidic and rich in cysteine (SPARC) is expressed in HCC, is positively correlated with cholesterol levels and promotes the invasive phenotype of HCC cells [53], [54]. SPARC can competitively bind with ApoE, thereby preventing its interaction with TRIM21 and helping to inhibit it...