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Figure 1. General scheme depicting the transport of terpenoids in plant cells. Lipophilic terpenes can passively diffuse through membranes [101,102,103], or they are transported by sequestration in vesicles or lipid droplets that fuse with the membrane, by carrier proteins, such as LTP proteins,...
Improvements in DNA vaccine design include the use of APC-specific promotors for transcriptional targeting, the arrangement of multiple antigen sequences, the co-delivery of molecular adjuvants to prevent tolerance induction, and strategies to circumvent potential inhibitory effects of the vector backbone...
In addition, both detection and differenti- ation of lesions become more challenging in complicated conditions of GB, such as acute and chronic inflammation and inclusion of stones or debris. This review classifies various GB lesions according to their US appearance and reviews the current status ...