We find that tyrosine is a stronger sticker than phenylalanine, whereas arginine is a context-dependent auxiliary sticker. In contrast, lysine weakens sticker–sticker interactions. Increasing the net charge per residue destabilizes phase separation while also weakening the strong coupling between single-...
Why on earth not? 36 items being treated in the same way ... says only one thing to me. Dec 26, 2018 at 11:36pm dutch(2548) @lastchance, It's much simpler (and faster, and just generally better looking!) than mine. But it's statistics seem a little worse. ...
Hsp90 is an essential molecular chaperone responsible for the folding and activation of hundreds of ‘client’ proteins, including the glucocorticoid receptor (GR). Previously, we revealed that Hsp70 and Hsp90 remodel the conformation of GR to regulate l
sector are lower than the corporate or government sectors, in line with trends in comparable countries (see U.S. Bureau of Labor Statistics,2021; UK Office for National Statistics,2021). For example, there is an estimated 40% gap between wages in NFPs and equivalent jobs in the public sect...
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Hsp90 is an essential molecular chaperone responsible for the folding and activation of hundreds of ‘client’ proteins, including the glucocorticoid receptor (GR). Previously, we revealed that Hsp70 and Hsp90 remodel the conformation of GR to regulate l
Mature B cell neoplasms, previously indolent non-Hodgkin lymphomas (iNHLs), are a heterogeneous group of malignancies sharing similar disease courses and treatment paradigms. Most patients with iNHL have an excellent prognosis, and in many, treatment can