The overall aim of this Thesis was to evaluate the safety and the efficacy of various models of anticoagulation that may be used in patients with a bleeding risk. The first study examined a low-dose anticoagulation model that was locally developed in Ume, Sweden in the 1980s. The primary ...
High-risk individuals are generally treated with “blood thinner” drugs including antiplatelet drugs like aspirin and clopidogrel or anticoagulants like heparin, warfarin, and dabigatran. While these drugs can reduce the risk of developing a clot, they fail to address many underlying risk factors and...
This selection bias may lead to an overestimation of the effectiveness of auto-SCT in pPCL; nonetheless, integration of novel therapies into induction, consolidation, and maintenance around auto-SCT would seem justified. Table 4. Results from the 2 largest retrospective series of pPCL patients ...
VEGF– 121, does not bind heparin and is freely diffusible. VEGF–165 has both bioavailability and biologic potency. VEGF–165 is the predominant isoform and the primary mediator of neovascularization in the eye [13]. All VEGF isoforms contain a plasmin cleavage site. Cleavage at this site crea...
34,40,64,79,80 Placebo controlled, randomized studies are currently underway to evaluate the role of fibrinogen repletion in major aortic surgery, and the results are eagerly awaited from a recently completed study (http://clinicaltrials.gov/show/NCT01475669). There is also a need to further...
13 It is a multicenter, all-comers registry investigating the effectiveness of the Pulsar-18 nitinol stent in the treatment of medium-length femoropopliteal lesions in 160 patients. Patients eligible for study inclusion included those with symptomatic peripheral artery disease of Rutherford cat...
01 Introduction Bad Medicine How the pharmaceutical industry is contributing to the global rise of antibiotic-resistant superbugs 1 How the pharmaceutical industry is contributing to the global rise of antibiotic-resistant superbugs Bad Medicine 2 How the pharmaceutical industry is contributing to the ...
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Chest X-rays and CT scans are used to assess mediastinal masses and pleural effusions and to evaluate potential kidney damage. ECG is vital for detecting cardiac abnormalities caused by hyperkalemia and hypocalcemia, especially since hyperkalemia can lead to life-threatening arrhythmias. The metabolic ...
The aim of this study was to evaluate the optimal extracorporeal life support (ECLS) configuration in primary cardiogenic shock, tailored to patient’s hemodynamic status and needed mechanical support. In particular, we sought to assess in which kind of patients the conversion from ECMO to CentriMag...