Analytical expressions are derived for the analysis of the accuracy of NMR determinations of conformational equilibrium constants, K. The relative error, 蟽K/K, shows a nearly linear increase with K for two commonly used modifications of the NMR approach to conformational analysis (based on ...
An easy way to include weak alignment constraints into NMR structure calculations The algorithm is used for the structure refinement of the HIV-1 Nef protein using 252 dipolar coupling restraints. The approach is compared to the ... HJ Sass,G Musco,SJ Stahl,... - 《Journal of Biomolecular ...
NMR spectroscopy is a unique and powerful technique that is suitable for characterizing various aspects of RNA and small molecules in the early stage of drug discovery. This webinar will provide an overview of the versatile roles of NMR spectroscopy in RNA drug discovery for providing the structural...
Besides the analysis blank, other negative controls such as a known reference material or an instrument blank can be utilized to validate the cleanliness of the analytical system. The use of such controls can help establish that the systems utilized for the analysis do not contain extractable compo...
to ~5%, but it remained large enough to permit accurate measurements of hybridization kinetics using NMR RD. Repeating the measurements at a different temperature also allowed us to test the robustness of the CS model. Based on a two-state fit of the adenine C8 RD data, which only reports ...
Changes in transmembrane helix alignment by arginine residues revealed by solid-state NMR experiments and coarse-grained MD simulations. A., and von Heijne, G. (2000) How proteins adapt to a membrane-water interface. Trends Biochem. Sci. 25, 429-434. Vitaly V. Vostrikov‡†, Benjamin A...
Terahertz spectroscopy for analysis of API polymorphs Advanced NMR techniques for structural elucidation of complex APIs Raman mapping for assessment of API distribution in formulations Building a Culture of Quality in API Sourcing Creating a culture of quality that extends beyond your organization to your...
aIn the 13C NMR analysis, the number of signals of 正在翻译,请等待...[translate] aAll experiments were conducted on A. bipunctata alongside H.axyridis, in order to allow comparison of data with a known natural 所有试验在A.做了。 bipunctata沿着H。[translate] ...
The use of H-1-C-13 and H-1-H-1 2D COSY correlation experiments substantially enhances the potential of the NMR procedure for determining the absolute conf... WP Unsworth 被引量: 30发表: 1993年 Chirality fingerprinting and geometrical determination of single-walled carbon nanotubes: Analysis of...
b) How do they differ from one another? How do you find gravimetric anaylsis? Describe how glow-discharge mass spectrometry is carried out. What are the advantages of this technique? What are shims in an NMR spectrometer and what is their purpose? Define gravimetric analysis and outline the ...