To analyze the differences not only in classic hematologic parameters but also in RBC subpopulations among δβ-thalassemia trait (δβ-TT), β-thalassemia trait (β-TT), and iron deficiency anemia (IDA) and to evaluate the role of fetal hemoglobin (HbF) in elevated RBC distribution width (...
41 Of 103 women with HbSS, HbSC, or HbSβ-thalassemia, 3 women (2.9%) experienced VTE. Compared with women with normal Hb status, the relative risk was 32.2 (95% CI, 9.7-107). The relationship between sickle cell trait, SCD, and VTE in pregnancy has recently been reviewed.42 In the...
The medical specialty of clinical genetics was established in the 1980s and 1990s in many European countries to diagnose these kinds of rare disorders and to counsel patients and families. In recent years, the attention of the genomics and genetics research community has shifted toward understanding...
People with thalassemia minor often do not have any symptoms. In sideroblastic anemia, the heme molecule of hemoglobin is not made correctly. This problem can be a genetic disorder, but it also can occur in people suffering from alcoholism, people exposed to toxins such as lead, or people ...