The quirky but fundamentally simple scale known as the pH scale is a measure of how acidic an aqueous solution is, or, in a different framing of the same chemical scenario, how basic or alkaline it is. To deter
How to determine if a pair of substances are likely to form a homogeneous solution? Suppose Fe3+(aq), Ca2+(aq) and Ba2+ are all present in the same solution. Fully describe a procedure whereby you could separate these ions from one another. ...
Each of these reaction rates is compared to the n-alkane reference point to determine the impact of branching and different functional groups. Although kinetic mechanisms typically assume that KHP dissociation rates are invariant of chemical environment , our QM results suggest that this rate can ...
Capping protein is known to contribute to branched actin network assembly in several ways. First, it prevents the elongation of filaments beyond a critical length at which they would easily buckle under load6,19,20. Second, it rapidly stops the non-productive elongation of filaments distant from ...
The specific activity of enzymes can be altered over long timescales in cells by synonymous mutations that alter a messenger RNA molecule’s sequence but not the encoded protein’s primary structure. How this happens at the molecular level is unknown. He
How can a pH titration curve be used to determine the acid dissociation constant of an unknown acid? Explain how a titration can be used to make a buffer. Upon dilution of a strong acid, will the pH of the solution increase, decrease, or stay the same? Calculate the pH at...
Every AIVC prediction could be substantiated with the corresponding multi-scale interactions that determine resulting states, e.g., understanding how a cellular subsystem or protein complex is disrupted in a diseased tissue can aid development of therapeutic interventions.118,119 The modular structure of...
If we’re examining thesamefunctional group, then applyingtrendsto determine the relative acidities is helpful. In this case, apply the trend that the more electronegative electron-withdrawing groups help to stabilize the negative charge in the conjugate base. The weaker the conjugate base, the str...
Can we one day use parts to create a whole?; (B) The main reason why we would like to control living systems is to control how one cell behaves and in this way, determine what it does e.g. differentiation. The tools to achieve such fates are only beginning to come of a...
Owing to this very strong interaction and the high protein concentrations required in the NMR experiments, we employed fluorescence spectroscopy to avoid ligand depletion effects and to ultimately determine the dissociation constant, Kd, of albicidin binding to AlbAS and AlbAL. The experimental read-...