The authors of this article have been spearheading an initiative to determine this type of crystal structure. The first step toward structure solution is to collect the diffraction data making sure that the satellite reflections are well separated from the main reflections. Once collected they can ...
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This study provides the first evidence for the existence of prefusion F-specific antibodies and their dominant contribution to the RSV-neutralizing activity of human sera. Article CAS PubMed PubMed Central Google Scholar Ngwuta, J. O. et al. Prefusion F-specific antibodies determine the ...
The locked rotation and translation functions have been developed to take advantage of the presence of NCS in this structure determination, which generally requires four steps. (i) The locked self-rotation function is used to determine the orientation of the NCS assembly in the crystal, relative ...
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1a). The MS-ring-subtracted particles were then used to determine high-resolution structures for the C-ring. Initial heterogeneous refinement resulted in five classes with different symmetries. One class contained 33-fold symmetry (13,081 particles), two classes contained 34-fold symmetry (15,301...
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et al. C-terminal regions of topoisomerase IIα and IIβ determine isoform-specific functioning of the enzymes in vivo. Nucleic Acids Res. 35, 3810–3822 (2007). Article CAS PubMed PubMed Central Google Scholar Ye, J. et al. TRF2 and apollo cooperate with topoisomerase 2 α to protect...
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To determine which capping-layer properties and processing conditions govern film stability, we employ a supervised-learning algorithm with a feature importance ranking. As model inputs, we include structural and chemical features of the organic molecules in the capping layers, derived from the PubChem...