31 Additionally, these conditions contribute to a reduction in peak systolic circumferential strain on CMR. Diabetes, hypertension and dyslipidemia can further result in a decrease in end-diastolic volume and stroke volume on CMR.31 FAPI PET imaging has mainly been studied retrospectively in ...
In skeletal muscle, calcium ions work at the level of actin (actin-regulated contraction). They move the troponin-tropomyosin complex off the binding sites, allowing actin and myosin to interact. All of this activity requires energy. Muscles use energy in the form of ATP. The energy from ATP...
in those with preserved endothelial function, troponin I concentrations were higher in patients who developed MACE during 7.0 ± 0.3 years of follow-up compared with those who did not (1.35 ng/l [interquartile range: 1.1 to 2.1 ng/l] vs. 0.7 ng/l [interquartile range: 0.7 to 1.1 ng/l...
Grade-specific biomechanical and neuromuscular alterations occur in running (for review, [18]). When compared to level running, DR is characterized by repeated and prolonged eccentric muscle actions of lower-limb muscles [14,24], lowered capacity of the stretch–shortening cycle [26,27], alteratio...
In skeletal muscle, calcium ions work at the level of actin (actin-regulated contraction). They move the troponin-tropomyosin complex off the binding sites, allowing actin and myosin to interact. All of this activity requires energy. Muscles use energy in the form of ATP. The energy from ATP...
from − 2.5 to − 8% in KE and PF; [9,10,15]) and the so-called “low-frequency fatigue”. The latter (usually investigated via muscle or nerve electrical stimulation) manifests through a decrease of the low (10–20 Hz)-to-high (50–100 Hz) frequency doublet ratio [93], ref...
In skeletal muscle, calcium ions work at the level of actin (actin-regulated contraction). They move the troponin-tropomyosin complex off the binding sites, allowing actin and myosin to interact. All of this activity requires energy. Muscles use energy in the form of ATP. The energy from ATP...
Elevated troponin levels are frequently observed in the elderly due to factors such as replacement fibrosis and renal dysfunction, necessitating careful interpretation in the clinical context. Furthermore, elderly ACS patients commonly present with multiple concurrent conditions, such as CKD, electrolyte ...
It begins as a TCA carbon flux block (increased lactate) in the early phase, mostly generated from a decrease of the anaplerotic reactions accumulating glutamate, tyrosine, and phenylalanine, but is likely retarded by the different conditions established during its onset (Figure 5, Table 1). ...
A high troponin value is commonly related to TTP instead of HUS. 8.2. Management The cornerstone of first-line therapy for acute TTP is based on therapeutic plasma exchange supplying the patient’s deficient ADAMTS13, performed daily until hemolysis and features related to organ involvement have ...