where ipaB was deleted do not have contact hemolytic activity.10,12 The previous data suggest a dual function for IpaB, one in concert with IpaC facilitating the transport of other Shigella virulence factors in host cells and the second inducing pyroptosis in infected cells without binding to ...
and assessed exactly how animals from the phylogenetic orderCarnivora–a group including animals often in close contact with humans like dogs, cats, and mink–evolved the ability to carry potentially deadly diseases without displaying any detectable illnesses themselves....
Interestingly, NLRC-4 patients have levels of IL-18 that are chronically strongly elevated. As IL-18 levels are also very high in (active) sJIA at time of MAS, they seem to play an important role in the development of MAS [95,[97], [98], [99]]. 10. Divergence in disease-course ...
to lyse the phagosomal membrane based on the results showing that IpaB alone can destabilize model membranes,11and that strains whereipaBwas deleted do not have contact hemolytic activity.10,12The previous data suggest a dual function for IpaB, one in concert with IpaC facilitating the transport...