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many countries provide extensive services to help people to stop smoking by offering a variety of effective behavioural and pharmacological therapies. However, many people who wish to stop smoking do not have access to or use stop smoking supports, and new modes of support, including the use...
2018), making atlases easily accessible is an increasingly difficult challenge. Cell-type centroids provide an efficient summary of active gene expression programs (Zeisel et al., 2018), but they are subject to batch effects (Tung et al., 2017) and discard expression variability. Although...
In this paper, we challenge the traditional way to simulate distributed systems by introducing a feedback loop in the workload model. Compared to using a pre-determined workload (historical record or generated) in the simulation, we let the workload adapt to the simulated performance of the sy...
39. Age-related functional changes in aminoacyl-tRNA synthetases have also been suggested to arise from conformational changes in some organisms69. A challenge in such studies will be to control for side reactions, such as increased oxidative damage that can occur to non-native conformations ...