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compounded medications) versus T4 medications (Synthroid, Levoxyl, Tirosint) alone. T4 is a precursor to T3, but some individuals do not convert T4 to T3 properly, and the T3 component is the metabolically active one.
The way I got better was by taking care of both deficiencies and it took me two years to do it! There are lots of studies online to peruse if this interests you. By the way, you cannot supplement with iron at the same time as Synthroid (Levothyroxine). Ferrous sulfate reduces thyroxine...