When smoothing data, it’s likely there’s no ground truth you’re aiming towards; just some noise in your measurements that hamper attempts to analyse it. Using the Whittaker smoother, we can vary λ to alter the level of noise removed from our data. Figure 1)Optical output of a galaxy...
This should encourage people to resort to SEC as a systematic approach to analyse sample hetero- geneity. Aggregates, contaminants and potentially different molecular arrangements of the protein of interest can be readily separated and quantified, with classical online UV detection. One should however...
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3. Results 3.1. The N-Terminal Intrinsically Disordered Region of MAGEA10 Is Responsible for Aberrant Migration in SDS-PAGE In order to study the molecular characteristics of the MAGEA10 protein, we designed various MAGEA10 mutants, as depicted in Figure 1A,B. The N-terminal part (the first ...
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It is well-suited to analyse complex multivariate data sets. Using PLS with two (or more) data sets or blocks, it is possible to establish linear combinations of variables which are predictive of linear combinations of variables in the other block [71,72]. The method finds factors in both ...
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