The optimised hardware configuration was tested on a real case scenario by comparing the manual versus automated approaches to analyse the immunosuppressant tacrolimus in the blood of 284 kidney transplant patients [2]. Passing Bablock regression ...
In addition, five Quality Control (QC) samples were prepared by combining 10 µL of each sample in a 2 mL vial and these pools were injected every seven samples to allow chromatogram alignment during data treatment. In-line UHPLC-UV-HRMS analysis was performed using a Dionex system ...