Topoisomerases interact with various proteins in the cell to accomplish these tasks. Post-translational modification of eukaryotic topoisomerases regulates their activation, localization and destruction. Small molecules and proteins can inhibit topoisomerase activity at different stages of the topoisomerase ...
I'm not sure I understand what you mean... can you look at this scaled down gui, and give an example of what your trying to accomplish... because I'm using a string to give the value, and then reading it compared to an integer value, and you still get the correct answer... so...