As the days get shorter and chillier in the northern hemisphere, those who choose to work out in the mornings might find it harder to get up and running. A new study in PNAS identifies a protein that, when missing, makes exercising in the cold that much harder—that is, at least in ...
Regulation of Wnt signaling by non-coding RNAs during osteoblast differentiation 2022, Differentiation Citation Excerpt : Studies suggested that modulating the levels of β-catenin could either positively or negatively regulate the canonical pathway (Polakis, 2000; Clevers, 2006; He et al., 2004). ...
While precisely editing the DNA in a cell's nucleus (blue) has become easier thanks to advances like CRISPR/Cas-9, it's been much harder to edit DNA in the mitochondria (red). Now, a new tool brings precision gene editing to mitochondrial DNA. Credit: Tslil Ast/Mootha Lab Scientists ...
which helps us understand what happens in soil or inside a human intestine," Straight added. "It helps us start to get a better image to work from when we talk about the role of microbes in the environment and the way competitive interactions structure microbial communities...
perfect construct validity. Whether in vivo models will be needed for every variant to be targeted is an interesting consideration. Hopefully, in vitro assays can be used to show efficacy and specificity for most guide RNAs, and in vivo efficiency can be demonstrated for a representative handful,...
Based on Kim's model [17] and Han's model [18] and combined with the summary of incentives to users in existing literature, the first sub-question and proposition can be proposed as follows: Sub-question 1: How do incentives to participants on the social commerce platform work in the ...
We expect that in such a case the occurrence of the other event may affect the number of stoppings attributed to the original event, making it harder to identify two times considered as arrival and departure times for the event. However, such cases where two big or medium scale events ...