54: How reliable is the chest X-ray to diagnose lung cancer in symptomatic patients? An audit of a single South London NHS TrustThe ability to target the epidermal growth factor receptor (EGFR) heralded an important development in the management of incurable non-small cell lung cancer (NSCLC)...
Estimated glomerular filtration rate (eGFR): This blood test measures how well your kidneys are filtering blood based on how muchcreatinine(a waste product created by the normal breakdown of muscles) is found in your blood. Urine albumin-creatinine ratio (uACR): This urine test measures how well...
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After obtaining MRI images, how do we optimally extract kidney volumes, and how reliable are those measurements? There are several approaches. The ellipsoidal method of estimating volume (TKV = (length × width × depth × pi/6) is easy to perform and readily available to clinicians who do ...
Therefore, there is an urgent need for appropriate preclinical models that are able to accurately mimic the clinical use of SBRT and provide reliable and translational information on radiobiology, efficacy, combinations and toxicities. The current poor performance of many investigational treatments suggests...
Cystatin C - a fast and reliable biomarker for glomerular filtration rate in head and neck cancer patients. Comparison of MDRD and CKD-EPI Formulas for Estimating Glomerular Filtration Rate in Elderly Preoperative Patients [4] Nonstandard abbreviations: CKD, chronic kidney disease; Scr, serum creatin...
For example, in people with metastatic lung cancer to the liver, patients with EGFR-positive tumors had a median survival of 11.7 months, while patients with EGFR-negative tumors had a median survival of only 4.1 months.5 The presence of liver metastases has also been linked to a poorer prog...
Prostate-specific antigen (PSA) is a reliable protein marker in blood for monitoring the response of prostate tumors to treatments (Kiper 2005; Fong 2009). Successful treatment will reduce PSA, and the levels may become undetectable. A rise in PSA can indicate that the therapy is not working ...
In addition, in EGFR/ALK-altered NSCLC, there was no difference in survival between patients with tumor PD-L1 < 1% vs. ≥ 1% [6]. Therefore, PD-L1 is not always reliable as a biomarker of immune efficacy in patients with advanced NSCLC. ICIs can also be used as adjuvant or ...
Here’s how to breath new life into that old reliable Sanger workhorse of yours:Get the new Applied Biosystems Minor Variant Finder (MVF) software. Prepare and sequence control and test samples using the same materials and procedures (same primers, same sample clean up method, same instrument,...