they have turned to royalties and, in very rare cases, private equity, but for the most part, the juniors are very challenged, especially the exploration companies. They’re hanging on by a thread. Essentially, a lot of their expenditures are really...
Because I didn’t have an email management provider, on the rare occasion when I did send out my newsletter, I just sent it through my Gmail. That’s where I sent all my other email, so why not mass-marketing messages too? In fact, I should have had my business email domain with p...
Rare Dis. 2020, 15, 149. [Google Scholar] [CrossRef] De Wit, J.; Bakker, L.A.; van Groenestijn, A.C.; van den Berg, L.H.; Schröder, C.D.; Visser-Meily, J.M.A.; Beelen, A. Caregiver burden in amyotrophic lateral sclerosis: A systematic review. Palliat. Med. 2018, 32...
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Repetitive sequences make up ~67% of the human genome [7], and are enriched within rare and common fragile sites (CFS), chromosomal regions susceptible to breakage, particularly under replication stress [8]. Our laboratory has proposed that the presence of multiple DNA polymerases with ...
This may be particularly true for rare diseases, where large-scale clinical evidence is hard to generate. While professional societies such as the ACMG provide guidance on the types of evidence and actions required to move forward with population screening [30], we suspect that there will never ...
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