A biosimilar is a biological product that is similar to a reference biologic (usually the originally approved product) and for which there are no clinically meaningful differences in terms of safety, purity, and potency. One example isAmjevita(adalimumab-atto), the first biosimilar approved forHumir...
SGLT2 inhibitors, sulfonylureas and insulin glargine. Participants achieved average A1C reductions between 1.8% and 2.4%. Weight loss was a secondary outcome in these studies.
Single injections of ADP and ATP induced flow increases which were more rapid in onset and of greater magnitude than those due to equimolar amounts of adenosine. Lowering the perfusate temperature prolonged coronary responses to ADP and ATP more than those to adenosine. Papaverine produced greater ...
On the subsequent days, the insulin utilization remains constant at 30 units per day. During the 24-h period that follows any injection of glargine U300, 80% (24 units) are provided by the administered dose. To this contribution it is necessary to add the 20% (6 units) that were not ...
How do detemir and glargine compare when added to oral agents in insulin-naïve patients with type 2 diabetes mellitus? (Nature Clinical Practice Endocrinology and Metabolism (2008) 4, (490-491) DOI: 10.1038/ncpendmet0900)Jennifer B. Marks...
Marks JB. How do detemir and glargine compare when added to oral agents in insulin-naive patients with type 2 diabetes mellitus? Nat Clin Pract Endocrinol Metab. 2008;4:490-491.Koenen C.: How do detemir and glargine compare when added to oral agents in insulin-naive patients with type...
A Study of How LY2605541 and Insulin Glargine Affect the Breakdown of Fat and Sugar in Type 1 DiabeticsEli LillyCompanyBone & Cancer Foundation
Applying eligibility criteria derived from the EDITION 1, 2 and 3 (Gla-300 vs. insulin glargine 100U/mL [Gla-100]) and BRIGHT (Gla-300 vs. insulin degludec) RCTs, we observed that only 17% (33345/191 218) of people captured in the real-world database would have been eligible for ...
Plakogiannis, RodaNathan, Joseph PRosenberg, Jack M