During this process a large number of water molecules appear to fill the spaces between the enzyme and the DNA. Once the cognate (recognition) sequence is found, much of the water is excluded as a highly redundant number of contacts evolve between the enzyme and the bases and phosphodiester ...
How much of a 4 mg/mL stock solution of X-GAL is required to prepare a 10 mL working solution of 4 g/mL X-GAL in DMSO?Dilution Equation:The solution that is observed after the addition of water into the stock solution called dilute...
molecule of the solvent. Work out how much volume a single would have in the box of your chosen density and size. Use :ref:`editconf<gmx editconf>` to place a box ofthat size around your single molecule. Then use :ref:`editconf<gmx editconf>` to move the molecule a little...
We can often find aggregate measures (such as in the yield example above) that avoid the need to dissecthowour system does what we want in too much detail. But it’s usually necessary to include more than one response in our optimization. In technical terms, this makes our problem one of...
First, we find that at a very low T - 4 K, only acoustic modes (A1-A3) contribute to spin and carrier relaxation. This is simply because the optical phonons are not excited at such low T (corresponding kBT ~ 0.34 meV much lower than optical energy ≳ 2 meV). At T ...
we apply our recently-developed first-principles real-time density-matrix dynamics (FPDM) approach17,18,19,20,21, to simulate spin relaxation and dephasing times of free electrons and holes in bulk CsPbBr3. FPDM approach was applied to disparate materials including silicon, (bcc) iron, transition...
For assembly with taxol, the tubulin molecule appears to be 0.15 nm ‘longer’ than it is in the tubulin–GDP lattice of standard microtubules. Taxol added after assembly induces a much smaller lengthwise change in the preformed microtubule lattice (0.04 nm). Significantly, although this taxol–...
In the presence of co-expressed parental HN to activate F (Fig.2E), A194T F is more activated and executes more fusion than parental F, but L234F F is much less readily activated than parental F. For parental F with HN, 50% fusion occurs at about 24 °C, shown by the blue dott...
Most strikingly, we observed a 3.5-fold larger rheobase in delayed firing GRPRexcit versus tonic firing GRPRinhib neurons, suggesting that these neurons should be much less excitable than the tonic firing GRPRinhib neurons. In addition, GRP neurons also had broader action potentials compared to ...
based on novel colloidal nanoparticles, which can be handled ‘in solution’ in much the same way as larger molecules. This enables researchers to apply the principles of synthetic supramolecular chemistry and the analytical tools of molecular science to control and characterise nanoscale structure with...