Among these we find the HxNy viruses (H2N2, H1N1, H1N2, etc., depending on the H or N antigen-proteins that express its metabolic synergy with living cells), mostly known as influenza viruses. The last serious pandemic provoked by this strain of virus was the 2009 H1N1 swine flu, which...
SARS-CoV-2SARS-CoV-2 Omicron variantThe article discusses the convergent evolution of the SARS-CoV-2 Spike protein, driven by immune escape from neutralizing antibodies. The mutations L455F and F456L, known as "FLips," have been acquired by multiple sublineages of the viru...
1. This research study evaluated potential immune molecular mimicry between the epitopes on the SARS-CoV19 S protein and retinal vascular endothelial cell proteins. 2. Bioinformatics was used to identify sequence similarities for potential immune response against the SARS-CoV19. 3. Significant protein ...
3D print of a spike protein of SARS-CoV-2, the virus that causes COVID-19—in front of a 3D print of a SARS-CoV-2 virus particle. The spike protein (foreground) enables the virus to enter and infect human cells. On the virus model, the virus surface (blue) is covered with spike ...
Coronaviruses Spike proteins SARS-CoV-2 RBD Mutations 1. Introduction SARS-CoV-2 belongs to the Coronavirus family, consisting of positive-sense, single-stranded RNA viruses that are lipid-enveloped [1]. In December 2019, SARS-CoV-2 infected its first patient, starting what would be a new pa...
Infection with SARS-CoV-2 leaves some people almost unaffected, while others develop life-threatening COVID-19 symptoms. So far, we do not understand exactly why symptoms and disease severity, especially in infections with the original variant, vary so s
2020). Nonetheless, the impact of this deletion on the gene function remains unclear. The viral proteins It has been noted that the SARS-CoV-2 genome contains 14 ORFs that encode about 27 different proteins, as indicated by Fig. 2a. Viral-associated proteins can be grouped into three ...
The production of infectious aerosols can vary wildly between individuals—and experts are exploring why in the COVID-19 era.
(RBD) of the SARS-CoV-2 spike protein. In experiments on mice, the researchers found that liposomes containing phospholipids functionalized with cobalt porphyrin groups can be combined with RBD proteins to make nanoparticles that may enter the antigen-presenting cells that elicit antibodies against ...
allowing recognition of many different viruses at once," says Grifoni. "While the SARS-CoV-2 Spike protein is the major target for antibodies, T cells can recognize additional antigens that are conserved across different coronaviruses. The combination of the two could be optimal in the design ...