The “context”, together with some Integration Architecture principles (within our Organization) will guide us in making many other choices as well… Do we try to use standard APIs and integration flows at any cost? No! Remember, we build for business needs; APIs should not dictate the ...
How these systems cooperate to compute heading, and the general principles of neural cue integration are current topics of research – for example, "divisive normalization" has been proposed as a canonical neural computation underlying reliability-weighted averaging38. One recent proposal is that an ...
Gas evolution is a vital process in many electrochemical systems. Bubbles appear as the result of primary elec- trode reactions in electrolysis, e.g., in chlor-alkali or water electrolysis, in the Hall-Hérault process for aluminum production1, and in direct-alcohol fuel cells2,3. They also...
However, they also felt that to be able to orient their teaching to the framework successfully, they needed to develop a thorough understanding of its principles and identify practical ways for applying these principles in their classroom practice. That same year, another study reported that one ...
Given the poor track record of public sector mechanization provision, the delivery of SAM should be firmly in the hands of the private sector that should be committed to SAM principles or otherwise be incentivized to the concept through smart subsidies. Improved information flows via smallholder ...
you are more likely to deliver a significant impact on your organization and advance in your career. We have also observed that when data scientists neglect one or more of these dimensions, they can get into difficult situations they must be mentored through or, in some cases, be managed out...
There are many gaps of knowledge, during the evolutionary selection of this fundamental biological process of gap junctional intercellular communication, of all the other genes crucial to the function and regulation of these connexin genes and the proteins of the gap junctions. After thriving in an ...
Its economic rise, in which GDP grew on average 10 percent each year for more than a decade, has come at the expense of its environment [2]. China is one of the world's largest sources of carbon emissions; the air quality of many of its major cities fails to meet international health...
Antagonists of GPCRs are—in many instances—effective pharmacochaperones: they restore cell surface expression provided that they enter cells and bind to folding intermediates. Pharmacochaperoning of SLC6 transporters is less readily achieved because the ionic conditions in the endoplasmic reticulum (ER)...
To achieve an oncological and func- tional outcome in the patient's best interest, it is critically important that sarcoma surgery is carried out with considerations for both biological and technical principles [20,21]. To obtain and improve the biological understanding of these tumors, ...