Background Sickle Cell Disease (SCD) is now one of the most common serious genetic condition in England. There is no reliable estimate of the total number of people living with SCD in the UK, to support commissioners and providers of services for people with SCD.Dormandy, ElizabethJames, ...
Many people havepersistent physical complaints, such as dizziness or pain, that don't appear to be symptoms of a medical condition. They are sometimes known as "medically unexplained symptoms" when they last for more than a few weeks, but doctors can't find a problem with the body that may...
some in the field have thought tumor-fighting CD8+ T cells come into suppressthe disease-causing immune response of CD4+ cells. But Han’s data strongly argues against that, instead pointing to CD8+ cells as a destructive force.“It kind of goes against these other, very ...
Blood transfusion remains an important therapeutic intervention in patients with sickle cell disease (SCD), aiming to both increase the oxygen carrying capacity of blood and to reduce the complications of vaso-occlusion. Simple, manual exchange and automated exchange can be effective in reducing the ...
Objectives This cross-sectional study examines to whom and how fully sickle cell disease (SCD) patients talk to others about sickle cell pain, how helpful it is to talk with others about these pain episodes, and the association between talking to others about sickle cell pain episodes and patie...
Research into sickle cell disease is personal, Hyacinth said, as his nephew has SCD and he and his son both havesickle cell trait. People with sickle cell trait inherit one sickle cell gene from a parent and typically do not have symptoms of SCD, but they can pass the trait on to their...
Sickle cell disease (SCD) is a common hereditary disease in Iran. In developed countries, newborn screening programs have been established to ensure early diagnosis, but in most developing countries, screening is not performed and the diagnosis is often delayed. The aim of the present work was ...
Patients with sickle cell disease have a single mutation in the gene that encodes hemoglobin, the protein that allows red blood cells to carry oxygen. The mutation tend to misshape red blood cells. Instead of the characteristic disc shape, cells become sickle-shaped, especially in low-oxygen co...
Sickle cell disease (SCD) is a family of inherited red blood cell disorders that occur when hemoglobin—the protein in red blood cells that carries oxygen throughout your body—takes on a C, or sickled, shape, instead of a healthy oval shape. Cells become hard and sticky, blocking blood ...
How I treat and manage strokes in sickle cell disease. Blood 2015;125: 3401-10... DeBaun,Michael,R.,... - 《Blood the Journal of the American Society of Hematology》 被引量: 20发表: 2015年 How I treat and manage strokes in sickle cell disease Kassim AA, Galadanci NA, Pruthi S, ...