Huntington's disease is a degenerative, hereditary, genetic illness similar to Parkinson's and it affects one in 10,000 in the population. Not only does it destroy the person - mind and body - but it destroys entire families as well. West Belfast journalist SHANE McKAY writes of the havoc...
Huntington disease: How many repeats does it take? 来自 NCBI 喜欢 0 阅读量: 9 作者: Hogarth,P. 摘要: Comment on Neurology. 2013 May 28;80(22):2022-7. 关键词: Humans Huntington Disease Nerve Tissue Proteins Phenotype Trinucleotide Repeat Expansion Male DOI: 10.1212/WNL.0b013e3182984b31...
She described how perspectives will change once the disease manifests, as had happened in her relatives with HD: “But as the disease shows itself more and more, becomes more evident, I have also seen that in my father and my brother, both of them have Huntington. Then you start to ...
To evaluate the potential for refinement, as well as its implementation in research, we analysed papers on murine models of Huntington's disease (HD) published between 1999 and 2009 (n = 233). Each study was classified according to a four-level severity scale, in terms of the disease stage...
Huntington’s disease obesity obsessive-compulsive disorder post-traumatic stress disorder schizophrenia sleep disorders suicidal behavior WHAT'S THE BEST BRAIN SUPPLEMENT? I hear this question often. Here's my answer: #1Live a brain-healthy lifestyle first (Be Brain Fit tells you how). ...
A hallmark of neurodegenerative diseases like Huntington's is the progressive death of nerve cells in the brain. The cells don't die quickly, though. They first start to disconnect from each other because their neurites—long finger-like extensions that
Pruning roses is not as complicated as it may seem, though it’s important to follow the right technique based on the type of rose you have. Here’s how—and when—to prune the roses in your garden! Sure, pruning roses can be a chore, but your efforts will be rewarded by a healthie...
Huntington's disease (HD) is a fatal neurodegenerative disease caused by an abnormal expansion of a CAG repeat in exon 1 of the HD gene on chromosome 4. The disease runs a debilitating and progressive course with an average survival of 15-25 years after disease onset. HD patients classically...
Huntington's disease: how intermediate are intermediate repeat lengths? Mov Disord 2012;27:1714e7.Squitieri, F., Jankovic, J., 2012. Huntington's disease: how intermediate are intermediate repeat lengths? Mov. Disord. 27, 1714-1717.Squitieri F and Jankovic J (2012). Huntington's disease: ...
Young peopleGenetic riskFamily communicationHuntington's diseaseUKFamily communication about adult-onset hereditary illness can be problematic, leaving some relatives inadequately informed or ignorant of their risk. Although studies have explored the barriers and facilitators in family communication about ...