When it comes to teaching reading, there are two main approaches: structured literacy and balanced literacy. While both methods have their pros and cons, it can be tough to decide which is the best for your classroom or child. In this blog post, we’ll break down the key differences betwe...
At diagnosis, the tumors are typically large (>3 cm), located in the tail or the body of the pancreas due to the high prevalence of alpha cells in this area and over 50% of them are metastatic [5]. Usually, glucagonomas are solitary tumors; however, less than 10% of glucagonomas ...
Antagonists of GPCRs are—in many instances—effective pharmacochaperones: they restore cell surface expression provided that they enter cells and bind to folding intermediates. Pharmacochaperoning of SLC6 transporters is less readily achieved because the ionic conditions in the endoplasmic reticulum (ER)...