In this species, several mutations decreasing the enzyme sensitivity to insecticides and thus responsible for resistance have been identified. After the sequencing of ChE-like genes in other species, repeated attempts to identify resistance mutations failed. These intriguing results raise the question of...
http://genomebiology.com/2000/1/2/reports/4013.1 Meeting report How many genes does it take to make a human being? Pablo D Rabinowicz, Erik Vollbrecht and Bruce May Address: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. E-mail: rabinowi@cshl.org ...
The team identified thousands of genes with altered expression patterns after light exposure, and 611 genes that had at least two-fold increases or decreases. Many of these genes have been previously linked to structural remodeling in the brain, suggesting that virtually the entire visual corte...
Like other species, we are the products of millions of years of adaptation. Now we're taking matters into our own hands.
Now he had the tools to prove it. Over the years, Lowell had developed an expertise in cutting-edge genetic engineering techniques that allowed him to target and delete specific genes and create new strains of “knockout” mice—meaning specific genes had been knocked out in an embryo, causin...
but with increasing global participation in athletics – and greater rewards to tempt athletes – it is more likely that individuals possessing the unique complement of genes for athletic performance can be identified early. ‘Was there someone like [sprinter] Michael Johnson in the 1920s?’ Dapena...
After researchers identified a pocket in HIF-2α1, Kaelin's team showed that a novel molecule could bind and inhibit the protein to cause tumour regression in mice2. And when the molecule was developed into a drug, Kaelin helped convince the developer to test its product on patients with ...
have been underrepresented by the PCR surveys. Moreover, it has been shown that several Hox genes (but notHox4) were involved during the regeneration process of the same sea cucumber species [32], reinforcing the finding thatHox4is absent. It has been suggested thatHgHox9identified by ...
“just as you are a person who has many functions in the population, not just one.” The phenomenon Cohen is describing is “pleiotropy,” the capacity of a single gene to have multiple, seemingly unrelated effects. It is one of the complexities of disease that has repeatedly frustrated ...
Secondly, several essential regulatory genes of cuproptosis have been identified to be associated with multiple RA processes, such as aberrant fibroblast-like synoviocytes (FLS) proliferation and inflammatory processes in various immune cells. Cuproptosis is a safe and non-invasive method of treatment ...