When I was a young medical student, an interesting discussion was going on about how antibody diversity was encoded; was the antibody molecule encoded in many genes, one for each specificity, or were they general adaptor proteins that were formed on an antigen template. I understood the argument...
As they did so, Aguayo-Mazzucato and her colleagues were struck by dramatic difference in the genes expressed by beta cells in animals of various ages. The researchers followed up to identify markers of aging in these cells, using several mouse models—one with impaired glucose tolerance (a con...
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are your genes, size, age, and sex. You can increase your metabolism somewhat by adding muscle mass and burning calories through exercise. Butyour metabolism ultimately plays a small role in any extra weight you carry. That has much more to do with how much you eat and how much you move...
2. The role of the γδ TCR: blowin' in the wind 2.1. Ligand recognition during thymic selection As in αβ T cells, a diverse TCR repertoire can be generated in γδ T cells by variable (V) gene combinations and formation of V(D)J junctions [6]. γδ T cells are conspicuously ...
Importantly, monounsaturates, such as oleate, are well known to attenuate palmitate toxicity (7). The experimental conditions used, however, will result in islet damage, allowing analysis of the mechanisms involved, many of which will be important in islet b-cell failure in diabetes. The RNA-...
Many genes are, indeed, transcribed in minimal amounts of mRNA per cell, which can cause large random fluctuations in biosynthesis. Genomic instability is another important source of inherent random variability, as shown in aged mice, which have a mutation rate of up to 104 per gene per cell...
3. Curcumin in Inflammation Induced Chronic Diseases Curcumin has been used as a remedy for the prevention and treatment of many organ and tissue disorders, most of which are associated with inflammation and oxidative stress. Curcumin alleviates oxidative stress, inflammation in chronic diseases and ...
Many people also turn to these pills to improve their sex lives, but are they really safe? In this article, we will explore the potential risks and benefits of enhancement pills. What Are Enhancement Pills? Enhancement pills are dietary supplements that claim to improve sexual function, ...
Hence, genes alone are not responsible for slow or stunted growth. The other major natural and environmental factors include; growth hormone deficiency and poor nutrition. An individual may be short despite having tall siblings and or parents due to a mutation, or alterations in the growth hormone...