Primary immune thrombocytopenia (ITP) is an immune-mediated bleeding disorder characterized by decreased platelet counts and an increased risk of bleeding. Multiple humoral and cellular immune abnormalities result in accelerated platelet destruction and
Hemolysis should be considered whena patient experiences acute jaundice or hematuria in the presence of anemia. Symptoms of chronic hemolysis include lymphadenopathy, hepatosplenomegaly, cholestasis, and choledocholithiasis. Other nonspecific symptoms include fatigue, dyspnea, hypotension, and tachycardia. What...
A 53-year old man with systemic lymphadenopathy and hepatosplenomegaly was diagnosed with diffuse large B cell-lymphoma after inguinal lymph node biopsy. A... H Katayama,M Takeuchi,T Yoshino,... - 《Leukemia & Lymphoma》 被引量: 45发表: 2001年 加载更多研究...
IVIg is another commonly used initial therapy that can raise the platelet counts rapidly in more than 80% of newly diagnosed ITP patients; however, it is relatively expensive and the response is usually transient [102]. A single-arm observational study suggested that bleeding severity, rather than...
(lymph) nodes. If there’s no cancer in the lymph nodes, a value of zero is given; if cancer is found in a small amount of nodes and isn’t yet severe, a number between 1–3 is given; and if it’s found in many nodes, then “late-stage” cancer is diagnosed, which is stage...
Edema and hepatomegaly and at times splenomegaly are common. X-rays show cardiomegaly, which on electrocardiogram is found to ... RS Goodman,M Goodman,N Gootman,... - 《Laryngoscope》 被引量: 86发表: 1976年 B-type natriuetic peptide measurements in diagnosing congestive heart failure in ...
aHLH diagnosis is established either by fulfilling a molecular genetic confirmation for a familial syndrome HLH gene mutation or by having five out of eight of the following criteria: (i) fever; (ii) splenomegaly; (iii) cytopenia (affecting more than two cell lineages); (iv) ...
and a blast phase. Most cases of CML are diagnosed in the chronic phase, during which patients might be asymptomatic or displaysigns and symptomssuch as fatigue, low-grade fever, elevated white blood cell count or splenomegaly, early satiety, left upper quadrant abdominal pain from spleen infarct...
On contrast-enhanced CT, the most important finding in patients with sarcoidosis is splenomegaly. However, small hypodense, ill-defined lesions with contrast-enhancement may also be encountered (Fig. 10). Usually the granulomas do not enhance more than healthy spleen; however, their attenuation is...
It is rare to have a presentation ofglandular fever in those over the age of 40 and glandular fever in this age group may present without a sore throat or lymphadenopathy. Older adults are less likely to have splenomegaly. Can I kiss my girlfriend if she has mono?