Colorectal cancer- microsatellite instability-high or mismatched repair deficient metastatic disease (CheckMate-142) Related questions What are monoclonal antibodies? How long does Opdivo take to work and how do you know if it's working? What is the difference between Opdivo and Keytruda?
I am abiochemistandmolecular biologiststudying the roles that microbes play in health and disease. I also teach cancer genetics to medical students and am interested in how the public understands science. While preventive and therapeutic vaccines are administered for different health care goals, they ...
Many of the recent advances in immuno-oncology have involved checkpoint inhibitors, including the breakthrough PD-1 inhibitors pembrolizumab (Keytruda®) and nivolumab (Opdivo), as well as PD-L1 and CTLA-4 inhibitors. This antibody-based therapy binds to immune-checkpoint proteins expressed on ...
Chemotherapy, together with radiation, may be administered before surgery for rectal cancer to reduce the size of tumors, or after surgery to kill any cancer cells left behind. It can also be used to shrink tumors in other parts of the body, relieving symptoms. Chemotherapy drugs may be given...