Complex RNA structures in 5′ UTRs, such as RNA G-quadruplexes, may serve as steric blocks to RNA structure unwinding by the scanning ribosome, eukaryotic initiation factor 4A (eIF4A) and other helicases. Internal ribosome entry sites (IRESs) recruit ribosomes to 5′ UTRs in a cap-indepen...
In a well-known model of rat hindlimb suspension (HS), the effect of both axial loading and ground reaction force on the rear part of the animal body is negligible. Interestingly, the physiological effects of these factors on the mammalian soleus muscle are different. Under...
The mechanism of editing is so far unknown. However, both,cis- andtrans-acting elements have been proposed to play a role. On thecis-acting side sequence elements immediately upstream of the respective site are necessary, putatively serving as binding sites fortrans-acting elements (Bock et al....
The mechanism of editing is so far unknown. However, both,cis- andtrans-acting elements have been proposed to play a role. On thecis-acting side sequence elements immediately upstream of the respective site are necessary, putatively serving as binding sites fortrans-acting elements (Bock et al....
In cancerous tissue, functional pathway predictions using PICRUSt revealed upregulation of pathways related to glycerophospholipid metabolism, ribosome biogenesis, and anaerobic respiration, while pathways related to inositol phosphate and flavonoid metabolism were downregulated [33,36,39]. A number of stud...
On CHROMagarTM Candida (CHROMagar, Paris, France), a differential agar medium, it is possible to distinguish a number of different Candida species by colour; as a result of distinct biochemical reactions, C. glabrata colonies appear white, pink to purple (Figure 1), in contrast to C. ...
1106 2 of 24 major intrinsic factor related to metabolic rate (R) is body mass (M), which has often been described by a simple power function, as follows: R = aMb, (1) where a is the scaling coefficient (or antilog of the intercept in a log-log plot) and b is the scaling expon...
Another important mechanism to down-regulate host gene expression is by destabilization of the mRNA. This can be achieved by decapping or endonucleolytic cleavage of the mRNA followed by exonucleolytic decay. Several DNA and RNA viruses target mRNAs that are undergoing ribosome assembly, and ...
On CHROMagarTM Candida (CHROMagar, Paris, France), a differential agar medium, it is possible to distinguish a number of different Candida species by colour; as a result of distinct biochemical reactions, C. glabrata colonies appear white, pink to purple (Figure 1), in contrast to C. ...