L. Han, Z. Zhao, CpG islands or CpG clusters: how to identify functional GC-rich regions in a genome? BMC Bioinformatics 10 (2009) 65.Han, L., Zhao, Z., 2009. CpG islands or CpG clusters: how to identify functi
Methylation of promoter-associated CGIs plays an important role in gene regulation and carcinogenesis. Because of the functional importance, multiple algorithms have been available for identifying CGIs in a sequence. Traditional algorithms are based on three sequence parameters (length, GC content, and...
classification of atherosclerosis as an important milestone in our quest to radically change the understanding and treatment of atherosclerotic disease. Similar content being viewed by others How the immune system shapes atherosclerosis: roles of innate and adaptive immunity...
The GC content and dinucleotide frequencies of many organisms have been determined (6). Because the sequences of many organisms have been elucidated it is now possible to generate complete restriction maps of entire genomes. Most of the completed genome sequences are available from the World Wide...
(PDF 48 kb) Abbreviations BAM: Binary alignment map; bp: Base pairs; GC%: Guanine–cytosine content; GEO: Gene expression omnibus; h: Hours; kb: Kilo-base; M: Millions; mn: Minutes; qRT-PCR: Quantitative reverse transcription polymerase chain reaction; SAM: Sequence alignment map ...
In this account, aberrant DNA methylation mechanism in the promoter regions of certain genes, which leads to silencing of some particular genes such as tumor suppressor and other cancer-related genes in carcinogenesis, is the most important epigenetic hallmark in human GC especially as a target for...
Antimicrobial resistance (AMR) is an urgent public health threat. Advancements in artificial intelligence (AI) and increases in computational power have resulted in the adoption of AI for biological tasks. This review explores the application of AI in ba
In this system, bacterially derived metabolites serve as important signals that continuously contribute to the proper function of the epithelial barrier and immune cells. Our understanding of the scope of these interactions is still in its infancy: most of the bacterial metabolome of the intestine ...
Codon and dicodon probabilities depend on the nucleotide composition, which can be approximated by the GC content of the locus19. We calculated the probability of a start codon without considering the effect of antisense overlap because this effect would be small in magnitude. Using the start and...
Hi everyone, I am just wonder if there is a way that I can take GC % database from somewhere and add it in Gbrowse 2.13 such as GC percent track from UCSC ( http://genome.ucsc.edu/cgi-bin/hgTracks?insideX=156&revCmplDisp=0&hgsid=167410927&hgt_doJsCommand=&position=chr1:178,...