A method of treating hemophilia A in a human subject requiring treatment of hemophilia A;Multiple doses of chimeric polypeptides, including (I) factor VIII (FVIII) polypeptide and (2) d 'domains of (II) von volt factor (VWF) and vWF fragments of vWF, includeAdministering to the subject at...
How we choose factor VIII to treat hemophilia In high-income countries, the large availability of coagulation factors for replacement therapy of patients with hemophilia A has raised the life expectanc... PM Mannucci,ME Mancuso,E Santagostino - 《Blood》 被引量: 83发表: 2012年 How we choose...
For this reason, the use of recombinant DNA-derived factor VIII (which is virus-free) to treat hemophilia A has generated considerable interest. Methods:... Lusher,M Jeanne,Arkin,... - 《New England Journal of Medicine》 被引量: 312发表: 1993年 Genetic induction of immune tolerance to hum...
Fibrinogen repletion, primarily with the use of fibrinogen concentrates for acquired bleeding, has been reported in clinical settings including surgery, trauma, and obstetrics (reviewed by Levy et al30). Trauma Fibrinogen levels are decreased in trauma patients on admission and are associated with poor...
More common causes of acquired fibrinogen disorders (right bottom box; causes leading to dysfibrinogenemia are indicated in italics) have already been ruled out at this step. &If an immunoassay is not available, then the PD-derived fibrinogen method is an accurate alternative in view of its ...
Because of this shortage, lupus patients found it difficult to obtain the drug to treat their lupus symptoms. India is a large manufacturer of hydroxychloroquine. Health insurance for lupus patients in India consists of the drug as a routine treatment protocol for patients. ...
Factor IX concentrate is used in hemophilia B ("Christmas disease"), which is caused by a deficiency of clotting factor IX. Ensuring a Safe Blood Supply There are many tests that are performed on blood to ensure its safety. These tests include checking for: Hepatitis B surface antigen Hepat...
Have a bleeding disorder, like hemophilia Take an anticoagulant medicine, like warfarin Have an allergy to metal Have a pacemaker Are pregnant Advantages of Acupuncture for Arthritis The advantages of acupuncture for arthritis include: It's a drug-free way to ease your pain. You could decrease yo...
and supplying a framework for proper referral to support pharmacists in their training. To i) test whether a research-informed training activity (short movie summarising analysis findings plus reflective workouts) fulfills NZ pharmacists’ annual continuing expert development needs including those associated...
May 9 - Pfizer:The pharma, which completed its $43 billion buyout of ADC specialist Seagen in December, has made the “difficult decision” to propose another round of staff reductions and role changes at the newly acquired company, a Pfizer spokesperson said. This time,...