HiFi sequencing is a single-molecule, real-time sequencing technology (SMRT) that provides incredible single-molecule read accuracy across long reads of tens of kilobases in length or more. HiFi reads are generated by combining information from multiple observations of a single DNA molecule, resulting...
How does the structure of DNA result in accurate replication? How does DNA electrophoresis work? How does DNA sequencing provide evidence of evolutionary relationships? What is high throughput DNA sequencing? How does DNA ligase work? How do stabilizing proteins work on the DNA?
Combining up to 48 independently addressable, high-capacity flow cells with powerful, integrated compute, PromethION 48 delivers flexible, on-demand access to terabases of sequencing data. View product View product PromethION 2 devices maintain the flexibility associated with ...
High Throughput Simulations Reveal how Sequence and Methylation Control DNA Looping and Self-AssociationGuidelines for submitting commentsPolicy: Comments that contribute to the discussion of the article will be posted within approximately three business days. We do not accept anonymous comments. Please ...
In recent years, next-generation sequencing (NGS) technologies have further expanded the boundaries of genotyping in agricultural breeding by providing cost-effective and high-throughput methods for sequencing entire genomes or large portions of genomes. New breeding techniques include genomic selection, wh...
Laboratories have been using ion channels in attempts at high-throughput DNA sequencing — individual nucleotides can be deduced from changes in electrical resistance as they snake through the pores of some ion channels. Many researchers are also interested in using ion channels as biosensors for the...
Droplet microfluidics enables the isolation of cells in picoliter-sized droplets, where appropriate chemistry can be added to achieve RNA-sequencing with high sensitivity. Recently, several groups achieved high-throughput scRNA-seq systems using commercial droplet technology, including inDrop86, Drop-seq...
This Cambrian-like explosion was made possible not only by advances in generative AI algorithms but also by the massive amounts of high-throughput DNA synthesis, sequencing, and screening data generated over the last decade. While the analysis of this data was once a bottleneck for many labs, ...
technologies that allow for deep, high-throughput, in-parallel DNA sequencing. Due to its high amount of information at ever lowering time and cost expense, 16S rDNA-Seq allows large, longitudinal, culture-free microbiome studies that permit a deep characterization of the investigated niches. This...
The pace of exome and genome sequencing is accelerating, with the identification of many new disease-causing mutations in research settings, and it is likely that whole exome or genome sequencing could have a major impact in the clinical arena in the rel