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Nanopore sequencing is fully scalable Nanopore sequencing is the only sequencing technology to enable real-time analysis in fully scalable formats. From the pocket-sized MinION to the high-throughput, population-scale PromethION — scale nanopore sequencing to suit any experimental needs.Prometh...
High-throughput DNA sequencing methods (e.g. metabarcoding) will provide new opportunities and challenges in this regard (Bush et al., 2017, Hering et al., 2018). Furthermore, openly accessible data repositories (Wilkinson et al., 2016) will contribute to the availability of biological data. ...
Figure 1. Deepening the understanding of enteric nervous system function and disease through high-throughput omics approaches. This review focuses on how data obtained by high-throughput approaches such as single cell sequencing deepen our understanding of cell identity, mechanisms of intercellular communic...
Droplet microfluidics enables the isolation of cells in picoliter-sized droplets, where appropriate chemistry can be added to achieve RNA-sequencing with high sensitivity. Recently, several groups achieved high-throughput scRNA-seq systems using commercial droplet technology, including inDrop86, Drop-seq...
Through the process of sharding, a way of partitioning, blockchain miners can maintain a consistent throughput throughout the network. Blockchain protocols, however, demand constant attention for their efficient functioning. BLOCKCHAIN PROTOCOL CHARACTERISTICS Each party maintains its own copy of the inf...
Antimicrobial resistance (AMR) is an urgent public health threat. Advancements in artificial intelligence (AI) and increases in computational power have resulted in the adoption of AI for biological tasks. This review explores the application of AI in ba
However, both bulk RNA-seq and scRNA-seq still fail to preserve the spatial organization of cells and their associated transcripts within the tissue. Parallelly, the advent of Next Generation Sequencing (NGS) enabled parallel multiplexed analysis of DNA sequences on a massive scale—tens of thousan...
Advances in high-throughput sequencing and in single-cell analysis indicate that better techniques to assess specificity are on the horizon. Validated reagents CRISPR-Cas has been harnessed for gene-editing experiments in many organisms to create cell lines and genetically engineered animals. There ...
When cells clump together, they restrict each other, reducing the throughput and ultimately compromising downstream results. Cell clumping also leads to lower recovery of target cells and can interfere with labeling. Certain methods of cell analysis such as flow cytometry require cells to be properly...