Learning how UV radiation causes DNA mutations is key to gaining a solid understanding of the mechanisms underlying skin cancer. This is also important when considering thedetrimental effects that UV light can have on your DNA-based experiments. In cells, DNA repair mechanisms can fix UV-damaged ...
The molecular building blocks that make up DNA absorb ultraviolet light so strongly that sunlight should deactivate them -- yet it does not. Now scientists have made detailed observations of a 'relaxation response' that protects these molecules, and the genetic information they encode, from UV ...
Too quick for the eye to see, UV light causes an electron to be transferred from one base to another on a single DNA strand. A base is the smallest unit of the genetic code, a small molecule that constitutes an individual "rung" on DNA's ladder. In a next-generation solar cell, lig...
Visible light doesn’t seem to cause muchdirectDNA damage, while UV does. Visible light also doesn’t increase the levels of the inflammatory cytokinesIL-8andTNFαwhile UV does. Blue light doesn’t significantly changethe levelsof p53, the tumour suppressor protein, while UV does. Visible light...
And, although UV light has more than enough firepower to make a photocopy, it can be very damaging to our eyes and skin. This is why photocopiers use a plain old incandescent or fluorescent bulb to flash light onto the original document. When the lamp in the copier is turned on, it ...
How does the skin around the eyes age? The ageing process of the tissue around the eye area is complex and involves changes in multiple anatomical layers, from the bony skeleton to the soft tissue and skin itself. As we age, the bony skeleton, including the orbital margin (i.e. the eye...
to protect their DNA from the Sun’s UV radiation.Sunlight is still the most important mechanism that helps sync our internal body clockto the outside world. As the days get longer in the spring, for example, the light-sensitive ipRGC cells in our eyes detect and respond to this change....
et al. Insight into the catalytic mechanism of DNA polymerase β: structures of intermediate complexes. Biochemistry 40, 5368–5375 (2001). The authors of this study show that it is metal B (in this case Cr(III)dNTP) alone that, in addition to inducing rapid conformational change, also ...
However, when there’s a change within our DNA or harm to it, a receptor can mutate. Since the directions in their DNA get merged genes do not work. Cells that need to be resting to divide and grow can be caused by this. How cancer starts They split and tell cells if it’s the ...
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