Introduction:In view of the vaso-occlusive pathophysiology affecting osseous micro-circulation, sickle cell disease (SCD) is well known to present with diverse skeletal and arthritic manifestations. With prolonged life-expectancy over the past decades, there has been a progressive increase in the ...
How does sickle cell anemia affect the kidneys?Sickle Cell Anemia:Sickle cell anemia is caused by a mutated gene that causes some of the red blood cells to assume a sickle shape, as opposed to the normal round shape. This can cause cells to become stuck in blood vessels and slow or ...
What is sickle cell disease? How does the structure of the red blood cells compare to normal cells?Genetic Disease :A disease that is caused by gene mutation is known as a genetic disease. The dominant or recessive mutated genes may become incapable to produce ...
Sickle cell disease affects the Black population in the U.S. more than it does the Hispanic population. The condition is much less common among white people. Liver disease and HIV, two other risk factors for PAH, also are more common among the Black population in the U.S. ...
Hemolytic anemia itself is rarely fatal, especially if treated early and properly, but the underlying conditions can be. Sickle cell disease. Sickle cell disease decreases life expectancy, although people with this condition are now living into their 50s and beyond, due to new treatments. Severe ...
Barriers to hematopoietic cell transplantation clinical trial participation of African American and black youth with sickle cell disease and their parents. J Pediatr Hematol Oncol. 2013;35:289–98. Article Google Scholar Parsons S, Thomson W, Cresswell K, Starling B, JE MD, Barbara Ansell ...
Drug abuse and addiction is a chronic disease that causes drug-seeking behavior and drug use despite negative consequences to the user and those around him. Though the initial decision to use drugs is voluntary, changes in the brain caused by repeated drug abuse can affect a person's self-con...
“A few groups of people are at a higher risk for zinc deficiencies, including those who’ve have had gastrointestinal surgery (including weight loss surgery), those with ulcerative colitis, Crohn’s disease, vegetarians, vegans, those pregnant or nursing, those with sickle cell disease, and inf...
A classic example of a genetic disease having a beneficial effect on survival is illustrated by the relationship between sickle-cell,(镶形血球)anemia (贫血症) and malaria(疟病). Only individuals having two copies of the sickle-cell gene and one normal gene are unaffected and, more importantly...
is wrong with the heart, so heart disease may not be detected until it is advanced and fewer treatment options are available. They also may suffer "silent heart attacks" because of the lack of warning signs. They may not know that they already have an advanced stage of the disease. ...