Transcription is a process where the DNA converts into RNA. Enzymes used in the transcription is RNA polymerase which assembles the nucleotide in RNA by using DNA as a template. In prokaryotes the transcription takes place in three steps I.e. initiation, elongation, and termination. In eukaryot...
How an RNA virus could insert DNA copies into a host's cell? How can it have DNA as an RNA virus? Explain. What is the role of RNA? How does protein synthesis differ between prokaryotes and eukaryotes? Is the difference between RNA and DNA that the RNA duplicates itself in the cytoplas...
Genetic studies in yeast indicate that RNA transcripts facilitate homology-directed DNA repair in a manner that is dependent on RAD52. The molecular basis for so-called RNA−DNA repair, however, remains unknown. Using reconstitution assays, we demonstr
Tatiana KentRichard T PomerantzNature Publishing GroupMcDevitt, S.; Rusanov, T.; Kent, T.; Chandramouly, G.; Pomerantz, R.T. How RNA transcripts coordinate DNA recombination and repair. Nat. Commun. 2018, 9, 1091. [CrossRef] [PubMed]...
Structure of a DNA:RNA hybrid duplex. Why RNase H does not cleave pure RNA. The solution structure of the DNA:RNA hybrid duplex d(GTCACATG):r(caugugac) has been determined by means of two-dimensional nuclear Overhauser effect (2D-N... OY Fedoroff,M Salazar,BR Reid - 《Journal of ...
A synthetic DNA enzyme catalyses the formation of a native phosphodiester bond between two RNA fragments, but the molecular details of the mechanism remained elusive. Research using computational and biochemical approaches now suggests that the DNA enzyme recruits two magnesium ions to assist in the ...
COVID-19 is a reminder of their destructive power, but they’re crucial to humans’ development and survival.
RNA function has long been known to be deeply intertwined with RNA structure.1 Recently, progress in high resolution static structural determination from x-ray crystallography,2 NMR,3 and cryo-EM4, 5 have given us deep insights into the intricacies of RNA structure beyond simple base pairing. ...
What does transcription mean in text? For text, it means a written or printed representation of something. For music, it means an arrangement of a piece of music. And, in biochemistry, transcription refers to the genetic information of DNA being copied onto a new strand of RNA. ...
While sequencing technologies also enable these applications, researchers choose fragment analysis because it has a faster turnaround time, higher sensitivity and is higher resolution. It is also more cost-effective due to its multiplexing capability; alleles for overl...